Pharmaceutical • Neuroprotective
Perceive Pharma develops novel small molecule neuroprotective therapeutics for ophthalmic diseases, including glaucoma.
Drug development • Localized drug delivery
Alessa Therapeutics develops localized drug delivery systems for early cancer treatment, focusing on minimizing systemic side effects.
Bioelectronic • Medicine
Cala Health develops non-invasive, FDA-cleared wearable devices for hand tremor relief, focusing on essential tremor and Parkinson's disease.
Corrective eye drops • Presbyopia treatment
Orasis Pharmaceuticals develops and commercializes corrective eye drops for treating presbyopia in adults.
Medical imaging • Coronary stenting
SpectraWAVE, Inc. develops advanced medical imaging systems to improve coronary stenting procedures and enhance clinical decision-making in the treatment of coronary artery disease.
Medical device • Non-invasive
HistoSonics is a medical device company that develops non-invasive histotripsy platforms, including the Edison® Histotripsy System, to mechanically destroy and liquefy targeted liver tumors using focused ultrasound.
Biotechnology • Genetic Medicines
Aro Biotherapeutics is a clinical stage biotech company specializing in the development of tissue-targeted genetic medicines, including a potential treatment for Pompe Disease and new therapies for autoimmune disorders, using their proprietary Centyrin-siRNA platform.
Biotechnology • Intraoperative Molecular Imaging Agents
On Target Laboratories develops and commercializes FDA-approved imaging agents for cancer surgeries, using near-infrared dye and targeting molecules to aid in detecting and resecting cancer cells.
Therapeutic Oncology • Solid Tumor Cancer Treatment
RefleXion Medical develops and commercializes SCINTIX therapy, a novel treatment for all stages of indicated solid tumor cancers, including metastatic disease, delivered via the RefleXion X1 platform.
Biopharmaceutical • Orthopedic Infections
Osteal Therapeutics is a clinical-stage biopharmaceutical company that develops novel musculoskeletal therapeutics to treat orthopedic infections, with its lead therapy, VT-X7, currently in Phase 2 development for chronic periprosthetic joint infections.
Biotechnology • Neuropsychiatric Disorders
Arialys Therapeutics is a biotechnology company that develops precision medicines to target pathogenic autoantibodies in the central nervous system, with a focus on treating neuropsychiatric diseases caused by autoimmunity.
Biotechnology • Autoimmune Diseases
ROME Therapeutics is a biotechnology company that develops breakthrough medicines for serious diseases, with a focus on an inhibitor of LINE-1 reverse transcriptase for autoimmune diseases, using their proprietary data science platform to identify active repeat elements and assess their roles in disease.
Biotechnology • Neurological Disorders
Rapport Therapeutics is a clinical-stage biotechnology company that develops precision neuromedicines for seizure and psychiatric disorders by targeting specific neuroanatomical regions, aiming to provide better alternatives to current treatments by reducing unwanted drug-target interactions.