Epigenome editing
Tune Therapeutics is a company specializing in epigenome editing to develop therapies for chronic diseases, including a clinical-stage drug for chronic Hepatitis B.
Biotechnology
Ouro Medicines is a biotechnology company developing immune reset therapeutics for chronic immune-mediated diseases, with a focus on B cell biology and T cell engagers.
Oral macrocycle drugs
Orbis Medicines develops oral macrocycle drugs as alternatives to biologic drugs using their nGen platform, which combines automated chemistry and machine learning.
Biotechnology
Avenzo Therapeutics is a biotechnology company developing oncology therapies, including a CDK2 inhibitor for advanced solid tumors and HR+/HER2-negative metastatic breast cancer.
Biotechnology
858 Therapeutics is a biotechnology company developing small molecule therapeutics for oncology and immunology, with a lead asset, ETX-19477, in Phase 1 trials for advanced solid tumors.
Serverless
DeltaStream, Inc. provides a serverless platform that simplifies the management, security, and processing of real-time streaming data for businesses.
Public-benefit
Second Front Systems (2F) develops mission-critical software solutions to enhance global security, primarily serving the U.S. government and international defense organizations like NATO.
World Labs develops advanced AI models that understand and interact with the 3D world for use by artists, designers, developers, engineers, game companies, and movie studios.
Gravel is a Jakarta-based digital platform that connects users with construction workers and provides services for hiring, contract management, on-demand home repairs, and ordering construction tools and materials, with plans for international expansion.
Public-benefit
Second Front Systems (2F) develops mission-critical software solutions to enhance global security, primarily serving the U.S. government and international defense organizations like NATO.
Augmented Reality
Mojo Vision is a startup that focuses on producing micro-LED panels for the next generation of displays, after initially aiming to produce augmented reality contact lenses.
Eyewear
Pair Eyewear is a customizable eyewear brand that offers over 1,000 "top frame" options, allowing customers to easily change their look, and has raised $75 million in a Series C funding round to enhance its manufacturing technology and expand globally.
Open-Source Software
Rocket.Chat is a Delaware-based startup that provides a Commercial Open Source Software (COSS) communications platform, enabling collaboration between colleagues, organizations, and customers while maintaining ownership of their conversations, with a focus on regulated industries such as government, healthcare, finance, education, and critical infrastructure.